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Cohesin, CTCF and lymphocyte antigen receptor locus rearrangement

The somatic recombination of lymphocyte antigen receptor loci is integral to lymphocyte differentiation and adaptive immunity. Here we review the relationship of this highly choreographed process with the zinc finger protein CTCF and with cohesin, a protein complex best known for its essential funct...

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Detalhes bibliográficos
Main Authors: Seitan, Vlad C, Krangel, Michael S, Merkenschlager, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352889/
https://ncbi.nlm.nih.gov/pubmed/22440186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.02.004
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