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Mechanics of T cell receptor gene rearrangement
The four T cell receptor genes (Tcra, Tcrb, Tcrg, Tcrd) are assembled by V(D)J recombination according to distinct programs during intrathymic T cell development. These programs depend on genetic factors, including gene segment order and recombination signal sequences. They also depend on epigenetic...
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676214/ https://ncbi.nlm.nih.gov/pubmed/19362456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.03.009 |
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