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Structural basis of translation inhibition by cadazolid, a novel quinoxolidinone antibiotic
Oxazolidinones are synthetic antibiotics used for treatment of infections caused by Gram-positive bacteria. They target the bacterial protein synthesis machinery by binding to the peptidyl transferase centre (PTC) of the ribosome and interfering with the peptidyl transferase reaction. Cadazolid is t...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6449356/ https://ncbi.nlm.nih.gov/pubmed/30948752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42155-4 |
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