NAD(+) metabolism governs the proinflammatory senescence-associated secretome

Cellular senescence is a stable growth arrest that is implicated in tissue ageing and cancer. Senescent cells are characterized by an upregulation of proinflammatory cytokines, which is termed the senescence-associated secretory phenotype (SASP). NAD(+) metabolism influences both tissue ageing and c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nat Cell Biol
Hauptverfasser: Nacarelli, Timothy, Lau, Lena, Fukumoto, Takeshi, Zundell, Joseph, Fatkhutdinov, Nail, Wu, Shuai, Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Schultz, David, Noma, Ken-ichi, Baur, Joseph A., Schug, Zachary, Tang, Hsin-Yao, Speicher, David W., David, Gregory, Zhang, Rugang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448588/
https://ncbi.nlm.nih.gov/pubmed/30778219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0287-4
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge