Harnessing mutual exclusivity between TP53 and ARID1 A mutations

по Wu, Shuai, Fatkhutdinov, Nail, Zhang, Rugang
Опубликовано в: Cell Cycle (2017)

Potential Therapeutic Targets in ARID1A-Mutated Cancer

по Bitler, Benjamin G., Fatkhutdinov, Nail, Zhang, Rugang
Опубликовано в: Expert Opin Ther Targets (2015)

Targeting RRM2 and Mutant BRAF is a Novel Combinatorial Strategy for Melanoma

по Fatkhutdinov, Nail, Sproesser, Katrin, Krepler, Clemens, Liu, Qin, Brafford, Patricia A., Herlyn, Meenhard, Aird, Katherine M., Zhang, Rugang
Опубликовано в: Mol Cancer Res (2016)

NAMPT inhibition suppresses cancer stem-like cells associated with therapy-induced senescence in ovarian cancer

по Nacarelli, Timothy, Fukumoto, Takeshi, Zundell, Joseph A., Fatkhutdinov, Nail, Jean, Stephanie, Cadungog, Mark G., Borowsky, Mark E., Zhang, Rugang
Опубликовано в: Cancer Res (2019)

HDAC6 inhibition synergizes with anti-PD-L1 therapy in ARID1A-inactivated ovarian cancer.

по Fukumoto, Takeshi, Fatkhutdinov, Nail, Zundell, Joseph A., Tcyganov, Evgenii N., Nacarelli, Timothy, Karakashev, Sergey, Wu, Shuai, Liu, Qin, Gabrilovich, Dmitry I., Zhang, Rugang
Опубликовано в: Cancer Res (2019)

N(6)-methylation of adenosine (m(6)A) of FZD10 mRNA contributes to PARP inhibitor resistance

по Fukumoto, Takeshi, Zhu, Hengrui, Nacarelli, Timothy, Karakashev, Sergey, Fatkhutdinov, Nail, Wu, Shuai, Liu, Pingyu, Kossenkov, Andrew V., Showe, Louise C., Jean, Stephanie, Zhang, Lin, Zhang, Rugang
Опубликовано в: Cancer Res (2019)

BET bromodomain inhibition synergizes with PARP inhibitor in epithelial ovarian cancer

по Karakashev, Sergey, Zhu, Hengrui, Yokoyama, Yuhki, Zhao, Bo, Fatkhutdinov, Nail, Kossenkov, Andrew V., Wilson, Andrew J., Simpkins, Fiona, Speicher, David, Khabele, Dineo, Bitler, Benjamin G., Zhang, Rugang
Опубликовано в: Cell Rep (2017)

Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence

по Zhao, Bo, Liu, Pingyu, Fukumoto, Takeshi, Nacarelli, Timothy, Fatkhutdinov, Nail, Wu, Shuai, Lin, Jianhuang, Aird, Katherine M., Tang, Hsin-Yao, Liu, Qin, Speicher, David W., Zhang, Rugang
Опубликовано в: Nat Commun (2020)

SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells

по Wu, Shuai, Fatkhutdinov, Nail, Fukumoto, Takeshi, Bitler, Benjamin G., Park, Pyoung Hwa, Kossenkov, Andrew V., Trizzino, Marco, Tang, Hsin-Yao, Zhang, Lin, Gardini, Alessandro, Speicher, David W., Zhang, Rugang
Опубликовано в: Nat Commun (2018)

HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci

по Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Tanizawa, Hideki, Fatkhutdinov, Nail, Bitler, Benjamin G., Le, Linh, Alicea, Gretchen, Yang, Ting-Lin, Johnson, F. Brad, Noma, Ken-ichi, Zhang, Rugang
Опубликовано в: J Cell Biol (2016)

ARID1A spatially partitions interphase chromosomes

по Wu, Shuai, Fatkhutdinov, Nail, Rosin, Leah, Luppino, Jennifer M., Iwasaki, Osamu, Tanizawa, Hideki, Tang, Hsin-Yao, Kossenkov, Andrew V., Gardini, Alessandro, Noma, Ken-ichi, Speicher, David W., Joyce, Eric F., Zhang, Rugang
Опубликовано в: Sci Adv (2019)

EZH2 inhibition sensitizes CARM1-high, homologous recombination proficient ovarian cancers to PARP inhibition

по Karakashev, Sergey, Fukumoto, Takeshi, Zhao, Bo, Lin, Jianhuang, Wu, Shuai, Fatkhutdinov, Nail, Park, Pyoung-Hwa, Semenova, Galina, Jean, Stephanie, Cadungog, Mark G., Borowsky, Mark E., Kossenkov, Andrew V., Liu, Qin, Zhang, Rugang
Опубликовано в: Cancer Cell (2020)

Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer

по Fukumoto, Takeshi, Park, Pyoung Hwa, Wu, Shuai, Fatkhutdinov, Nail, Karakashev, Sergey, Nacarelli, Timothy, Kossenkov, Andrew V., Speicher, David W., Jean, Stephanie, Zhang, Lin, Wang, Tian-Li, Shih, Ie-Ming, Conejo-Garcia, Jose R., Bitler, Benjamin G., Zhang, Rugang
Опубликовано в: Cell Rep (2018)

ARID1A promotes genomic stability through protecting telomere cohesion

по Zhao, Bo, Lin, Jianhuang, Rong, Lijie, Wu, Shuai, Deng, Zhong, Fatkhutdinov, Nail, Zundell, Joseph, Fukumoto, Takeshi, Liu, Qin, Kossenkov, Andrew, Jean, Stephanie, Cadungog, Mark G., Borowsky, Mark E., Drapkin, Ronny, Lieberman, Paul M., Abate-Shen, Cory T., Zhang, Rugang
Опубликовано в: Nat Commun (2019)

NAD(+) metabolism governs the proinflammatory senescence-associated secretome

по Nacarelli, Timothy, Lau, Lena, Fukumoto, Takeshi, Zundell, Joseph, Fatkhutdinov, Nail, Wu, Shuai, Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Schultz, David, Noma, Ken-ichi, Baur, Joseph A., Schug, Zachary, Tang, Hsin-Yao, Speicher, David W., David, Gregory, Zhang, Rugang
Опубликовано в: Nat Cell Biol (2019)

Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma

по Wu, Shuai, Fukumoto, Takeshi, Lin, Jianhuang, Nacarelli, Timothy, Wang, Yemin, Ong, Dionzie, Liu, Heng, Fatkhutdinov, Nail, Zundell, Joseph A., Karakashev, Sergey, Zhou, Wei, Schwartz, Lauren E., Tang, Hsin-Yao, Drapkin, Ronny, Liu, Qin, Huntsman, David G., Kossenkov, Andrew V., Speicher, David W., Schug, Zachary T., Van Dang, Chi, Zhang, Rugang
Опубликовано в: Nat Cancer (2021)