Harnessing mutual exclusivity between TP53 and ARID1 A mutations

Por Wu, Shuai, Fatkhutdinov, Nail, Zhang, Rugang
Publicado no Cell Cycle (2017)

Potential Therapeutic Targets in ARID1A-Mutated Cancer

Por Bitler, Benjamin G., Fatkhutdinov, Nail, Zhang, Rugang
Publicado no Expert Opin Ther Targets (2015)

Targeting RRM2 and Mutant BRAF is a Novel Combinatorial Strategy for Melanoma

Por Fatkhutdinov, Nail, Sproesser, Katrin, Krepler, Clemens, Liu, Qin, Brafford, Patricia A., Herlyn, Meenhard, Aird, Katherine M., Zhang, Rugang
Publicado no Mol Cancer Res (2016)

NAMPT inhibition suppresses cancer stem-like cells associated with therapy-induced senescence in ovarian cancer

Por Nacarelli, Timothy, Fukumoto, Takeshi, Zundell, Joseph A., Fatkhutdinov, Nail, Jean, Stephanie, Cadungog, Mark G., Borowsky, Mark E., Zhang, Rugang
Publicado no Cancer Res (2019)

HDAC6 inhibition synergizes with anti-PD-L1 therapy in ARID1A-inactivated ovarian cancer.

Por Fukumoto, Takeshi, Fatkhutdinov, Nail, Zundell, Joseph A., Tcyganov, Evgenii N., Nacarelli, Timothy, Karakashev, Sergey, Wu, Shuai, Liu, Qin, Gabrilovich, Dmitry I., Zhang, Rugang
Publicado no Cancer Res (2019)

N(6)-methylation of adenosine (m(6)A) of FZD10 mRNA contributes to PARP inhibitor resistance

Por Fukumoto, Takeshi, Zhu, Hengrui, Nacarelli, Timothy, Karakashev, Sergey, Fatkhutdinov, Nail, Wu, Shuai, Liu, Pingyu, Kossenkov, Andrew V., Showe, Louise C., Jean, Stephanie, Zhang, Lin, Zhang, Rugang
Publicado no Cancer Res (2019)

BET bromodomain inhibition synergizes with PARP inhibitor in epithelial ovarian cancer

Por Karakashev, Sergey, Zhu, Hengrui, Yokoyama, Yuhki, Zhao, Bo, Fatkhutdinov, Nail, Kossenkov, Andrew V., Wilson, Andrew J., Simpkins, Fiona, Speicher, David, Khabele, Dineo, Bitler, Benjamin G., Zhang, Rugang
Publicado no Cell Rep (2017)

Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence

Por Zhao, Bo, Liu, Pingyu, Fukumoto, Takeshi, Nacarelli, Timothy, Fatkhutdinov, Nail, Wu, Shuai, Lin, Jianhuang, Aird, Katherine M., Tang, Hsin-Yao, Liu, Qin, Speicher, David W., Zhang, Rugang
Publicado no Nat Commun (2020)

SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells

Por Wu, Shuai, Fatkhutdinov, Nail, Fukumoto, Takeshi, Bitler, Benjamin G., Park, Pyoung Hwa, Kossenkov, Andrew V., Trizzino, Marco, Tang, Hsin-Yao, Zhang, Lin, Gardini, Alessandro, Speicher, David W., Zhang, Rugang
Publicado no Nat Commun (2018)

HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci

Por Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Tanizawa, Hideki, Fatkhutdinov, Nail, Bitler, Benjamin G., Le, Linh, Alicea, Gretchen, Yang, Ting-Lin, Johnson, F. Brad, Noma, Ken-ichi, Zhang, Rugang
Publicado no J Cell Biol (2016)

ARID1A spatially partitions interphase chromosomes

Por Wu, Shuai, Fatkhutdinov, Nail, Rosin, Leah, Luppino, Jennifer M., Iwasaki, Osamu, Tanizawa, Hideki, Tang, Hsin-Yao, Kossenkov, Andrew V., Gardini, Alessandro, Noma, Ken-ichi, Speicher, David W., Joyce, Eric F., Zhang, Rugang
Publicado no Sci Adv (2019)

EZH2 inhibition sensitizes CARM1-high, homologous recombination proficient ovarian cancers to PARP inhibition

Por Karakashev, Sergey, Fukumoto, Takeshi, Zhao, Bo, Lin, Jianhuang, Wu, Shuai, Fatkhutdinov, Nail, Park, Pyoung-Hwa, Semenova, Galina, Jean, Stephanie, Cadungog, Mark G., Borowsky, Mark E., Kossenkov, Andrew V., Liu, Qin, Zhang, Rugang
Publicado no Cancer Cell (2020)

Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer

Por Fukumoto, Takeshi, Park, Pyoung Hwa, Wu, Shuai, Fatkhutdinov, Nail, Karakashev, Sergey, Nacarelli, Timothy, Kossenkov, Andrew V., Speicher, David W., Jean, Stephanie, Zhang, Lin, Wang, Tian-Li, Shih, Ie-Ming, Conejo-Garcia, Jose R., Bitler, Benjamin G., Zhang, Rugang
Publicado no Cell Rep (2018)

ARID1A promotes genomic stability through protecting telomere cohesion

Por Zhao, Bo, Lin, Jianhuang, Rong, Lijie, Wu, Shuai, Deng, Zhong, Fatkhutdinov, Nail, Zundell, Joseph, Fukumoto, Takeshi, Liu, Qin, Kossenkov, Andrew, Jean, Stephanie, Cadungog, Mark G., Borowsky, Mark E., Drapkin, Ronny, Lieberman, Paul M., Abate-Shen, Cory T., Zhang, Rugang
Publicado no Nat Commun (2019)

NAD(+) metabolism governs the proinflammatory senescence-associated secretome

Por Nacarelli, Timothy, Lau, Lena, Fukumoto, Takeshi, Zundell, Joseph, Fatkhutdinov, Nail, Wu, Shuai, Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Schultz, David, Noma, Ken-ichi, Baur, Joseph A., Schug, Zachary, Tang, Hsin-Yao, Speicher, David W., David, Gregory, Zhang, Rugang
Publicado no Nat Cell Biol (2019)