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Potential Therapeutic Targets in ARID1A-Mutated Cancer
ARID1A is a subunit of the Switch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex that regulates gene expression by controlling gene accessibility. ARID1A shows one of the highest mutation rates across different human cancer types. For example, ARID1A is mutated in ~50% of ovarian cle...
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| Publicado no: | Expert Opin Ther Targets |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4674066/ https://ncbi.nlm.nih.gov/pubmed/26125128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2015.1062879 |
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