Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization

Senescence is induced by various stimuli such as oncogene expression and telomere shortening, referred to as oncogene-induced senescence (OIS) and replicative senescence (RS), respectively, and accompanied by global transcriptional alterations and 3D genome reorganization. Here, we demonstrate that...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Iwasaki, Osamu, Tanizawa, Hideki, Kim, Kyoung-Dong, Kossenkov, Andrew, Nacarelli, Timothy, Tashiro, Sanki, Majumdar, Sonali, Showe, Louise C., Zhang, Rugang, Noma, Ken-ichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908677/
https://ncbi.nlm.nih.gov/pubmed/31831736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13604-5
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