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Selective Hydrogen Atom Abstraction via Induced Bond Polarization: The Direct α-Arylation of Alcohols via Photoredox, HAT and Nickel Catalysis

The combination of nickel metallaphotoredox catalysis, hydrogen atom transfer catalysis, and a Lewis acid activation mode, has led to the development of an arylation protocol for the selective functionalization of alcohol α-hydroxy C–H bonds. This approach employs zinc-mediated alcohol deprotonation...

詳細記述

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書誌詳細
出版年:Angew Chem Int Ed Engl
主要な著者: Twilon, Jack, Christensen, Melodie, DiRocco, Daniel A., Ruck, Rebecca T., Davies, Ian W., MacMillan, David W. C.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448405/
https://ncbi.nlm.nih.gov/pubmed/29490112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201800749
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