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Enantioselective Decarboxylative Arylation of α-Amino Acids via the Merger of Photoredox and Nickel Catalysis

An asymmetric decarboxylative C(sp(3))–C(sp(2)) cross-coupling has been achieved via the synergistic merger of photoredox and nickel catalysis. This mild, operationally simple protocol transforms a wide variety of naturally abundant α-amino acids and readily available aryl halides into valuable chir...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Zuo, Zhiwei, Cong, Huan, Li, Wei, Choi, Junwon, Fu, Gregory C., MacMillan, David W. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862596/
https://ncbi.nlm.nih.gov/pubmed/26849354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b13211
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