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Merging photoredox with nickel catalysis: Coupling of α-carboxyl sp(3)-carbons with aryl halides

Over the past 40 years, transition metal catalysis has enabled bond formation between aryl and olefinic (sp(2)) carbons in a selective and predictable manner with high functional group tolerance. Couplings involving alkyl (sp(3)) carbons have proven more challenging. Here, we demonstrate that the sy...

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Publicado en:Science
Main Authors: Zuo, Zhiwei, Ahneman, Derek T., Chu, Lingling, Terrett, Jack A., Doyle, Abigail G., MacMillan, David W. C.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296524/
https://ncbi.nlm.nih.gov/pubmed/24903563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1255525
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