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C–H functionalization of amines with aryl halides by nickel-photoredox catalysis

We describe the functionalization of α-amino C–H bonds with aryl halides using a combination of nickel and photoredox catalysis. This direct C–H, C–X coupling uses inexpensive and readily available starting materials to generate benzylic amines, an important class of bioactive molecules. Mechanistic...

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Bibliografski detalji
Izdano u:Chem Sci
Glavni autori: Ahneman, Derek T., Doyle, Abigail G.
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207500/
https://ncbi.nlm.nih.gov/pubmed/28058105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02815b
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