Genome-scale integrated analysis to identify prospective molecular mechanisms and therapeutic targets in isocitrate dehydrogenase 2 R140Q-mutated acute myeloid leukemia

The aim of the present study was to identify potential molecular mechanisms and therapeutic targets in regards to isocitrate dehydrogenase 2 (IDH2) R140Q-mutated acute myeloid leukemia (AML). An RNA sequencing dataset of IDH2 wild-type and R140Q-mutated adult de novo AML bone marrow samples was obta...

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Bibliografiska uppgifter
I publikationen:Oncol Rep
Huvudupphovsmän: Huang, Rui, Liao, Xiwen, Li, Jing, Wei, Jiemin, Su, Xiayun, Lai, Xiaoxuan, Liu, Beicai, Zhu, Fangxiao, Huang, Yumei, Li, Qiaochuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2019
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448125/
https://ncbi.nlm.nih.gov/pubmed/30896832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7075
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