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Identification of Key Genes and Pathways Associated with RUNX1 Mutations in Acute Myeloid Leukemia Using Bioinformatics Analysis

BACKGROUND: RUNXl plays a key regulatory role in the process of hematopoiesis and is a common target for multiple chromosomal translocations in human acute leukemia. Mutations of RUNX1 gene can lead to acute leukemia and affect the prognosis of AML patients. We aimed to identify pivotal genes and pa...

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Dades bibliogràfiques
Publicat a:Med Sci Monit
Autors principals: Zhu, Fangxiao, Huang, Rui, Li, Jing, Liao, Xiwen, Huang, Yumei, Lai, Yongrong
Format: Artigo
Idioma:Inglês
Publicat: International Scientific Literature, Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186152/
https://ncbi.nlm.nih.gov/pubmed/30289875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM910916
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