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Identification of key pathways and genes in TP53 mutation acute myeloid leukemia: evidence from bioinformatics analysis

BACKGROUND: Tumor protein p53 (TP53) mutations are not only a risk factor in acute myeloid leukemia (AML) but also a potential biomarker for individualized treatment options. This study aimed to investigate potential pathways and genes associated with TP53 mutations in adult de novo AML. METHODS: An...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Huang, Rui, Liao, Xiwen, Li, Qiaochuan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749383/
https://ncbi.nlm.nih.gov/pubmed/29343974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S156003
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