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Functional Classification of TP53 Mutations in Acute Myeloid Leukemia

Mutations of the TP53 gene occur in a subset of patients with acute myeloid leukemia (AML) and confer an exceedingly adverse prognosis. However, whether different types of TP53 mutations exert a uniformly poor outcome has not been investigated yet. Here, we addressed this issue by analyzing data of...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Dutta, Sayantanee, Pregartner, Gudrun, Rücker, Frank G., Heitzer, Ellen, Zebisch, Armin, Bullinger, Lars, Berghold, Andrea, Döhner, Konstanze, Sill, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139772/
https://ncbi.nlm.nih.gov/pubmed/32164171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030637
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