Loading...
Isocitrate dehydrogenase inhibitors in acute myeloid leukemia
Isocitrate dehydrogenase (IDH) is a key enzyme involved in the conversion of isocitrate to α-ketoglutarate (α-KG) in the tricarboxylic acid (TCA) cycle. IDH mutation produces a neomorphic enzyme, which can lead to the abnormal accumulation of R-2-HG and promotes leukemogenesis. IDH mutation occurs i...
Na minha lista:
| Udgivet i: | Biomark Res |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6806510/ https://ncbi.nlm.nih.gov/pubmed/31660152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-019-0173-z |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|