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Isocitrate dehydrogenase mutations in leukemia

Recent genome-wide discovery studies have identified a spectrum of mutations in different malignancies and have led to the elucidation of novel pathways that contribute to oncogenic transformation. The discovery of mutations in the genes encoding isocitrate dehydrogenase (IDH) has uncovered a critic...

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Bibliografische gegevens
Hoofdauteurs: McKenney, Anna Sophia, Levine, Ross L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754251/
https://ncbi.nlm.nih.gov/pubmed/23999441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67266
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