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Isocitrate dehydrogenase mutations in leukemia
Recent genome-wide discovery studies have identified a spectrum of mutations in different malignancies and have led to the elucidation of novel pathways that contribute to oncogenic transformation. The discovery of mutations in the genes encoding isocitrate dehydrogenase (IDH) has uncovered a critic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754251/ https://ncbi.nlm.nih.gov/pubmed/23999441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67266 |
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