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Isocitrate dehydrogenase mutations in leukemia

Recent genome-wide discovery studies have identified a spectrum of mutations in different malignancies and have led to the elucidation of novel pathways that contribute to oncogenic transformation. The discovery of mutations in the genes encoding isocitrate dehydrogenase (IDH) has uncovered a critic...

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Detalhes bibliográficos
Main Authors: McKenney, Anna Sophia, Levine, Ross L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754251/
https://ncbi.nlm.nih.gov/pubmed/23999441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67266
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