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Isocitrate dehydrogenase mutations in myeloid malignancies
Alterations to genes involved in cellular metabolism and epigenetic regulation are implicated in the pathogenesis of myeloid malignancies. Recurring mutations in isocitrate dehydrogenase (IDH) genes are detected in approximately 20% of adult patients with acute myeloid leukemia (AML) and 5% of adult...
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| Publicado no: | Leukemia |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5292675/ https://ncbi.nlm.nih.gov/pubmed/27721426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.275 |
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