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Mutation Analysis of Isocitrate Dehydrogenase in Acute Lymphoblastic Leukemia

Background: Mutations at arginine 132 of isocitrate dehydrogenase 1/2 (IDH1/2) have recently been demonstrated to be recurrent gene alterations in acute myeloid leukemia (AML). Subsequently, this mutation was also found in a variety of other hematologic malignancies, including myelodysplastic syndro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Yiqun, Wei, Hui, Tang, Kejing, Lin, Dong, Zhang, Cuiping, Mi, Yingchang, Wang, Lin, Wang, Cuicui, Wang, Min, Wang, Jianxiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422558/
https://ncbi.nlm.nih.gov/pubmed/22809434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2011.0323
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