Spectrum of somatic mutations detected by targeted next-generation sequencing and their prognostic significance in adult patients with acute lymphoblastic leukemia

Target-specific next-generation sequencing technology was used to analyze 112 genes in adult patients with acute lymphoblastic leukemia (ALL). This sequencing mainly focused on the specific mutational hotspots. Among the 121 patients, 93 patients were B-ALL (76.9%), and 28 patients (23.1%) were T-AL...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Feng, Juan, Li, Yan, Jia, Yujiao, Fang, Qiuyun, Gong, Xiaoyuan, Dong, Xiaobao, Ru, Kun, Li, Qinghua, Zhao, Xingli, Liu, Kaiqi, Wang, Min, Tian, Zheng, Jia, Yannan, Wang, Ying, Lin, Dong, Wei, Hui, Tang, Kejing, Mi, Yingchang, Wang, Jianxiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331692/
https://ncbi.nlm.nih.gov/pubmed/28245838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0431-1
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