Spectrum of somatic mutations detected by targeted next-generation sequencing and their prognostic significance in adult patients with acute lymphoblastic leukemia

Target-specific next-generation sequencing technology was used to analyze 112 genes in adult patients with acute lymphoblastic leukemia (ALL). This sequencing mainly focused on the specific mutational hotspots. Among the 121 patients, 93 patients were B-ALL (76.9%), and 28 patients (23.1%) were T-AL...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Hematol Oncol
Main Authors: Feng, Juan, Li, Yan, Jia, Yujiao, Fang, Qiuyun, Gong, Xiaoyuan, Dong, Xiaobao, Ru, Kun, Li, Qinghua, Zhao, Xingli, Liu, Kaiqi, Wang, Min, Tian, Zheng, Jia, Yannan, Wang, Ying, Lin, Dong, Wei, Hui, Tang, Kejing, Mi, Yingchang, Wang, Jianxiang
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2017
נושאים:
Letter to the Editor
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331692/
https://ncbi.nlm.nih.gov/pubmed/28245838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0431-1
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