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Targeting Activated Synovial Fibroblasts in Rheumatoid Arthritis by Peficitinib
Background: Synovial fibroblasts (SF) play a major role in the pathogenesis of rheumatoid arthritis (RA) and develop an aggressive phenotype destroying cartilage and bone, thus termed RASF. JAK inhibitors have shown to be an efficient therapeutic option in RA treatment, but less is known about the e...
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| Veröffentlicht in: | Front Immunol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6448044/ https://ncbi.nlm.nih.gov/pubmed/30984167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00541 |
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