The antidiabetic drug metformin prevents and reverses neuropathic pain and spinal cord microglial activation in male but not female mice

Metformin is a widely prescribed drug used in the treatment of type II diabetes. While the drug has many mechanisms of action, most of these converge on AMP activated protein kinase (AMPK), which metformin activates. AMPK is a multifunctional kinase that is a negative regulator of mechanistic target...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Pharmacol Res
Autores principales: Inyang, Kufreobong E, Szabo-Pardi, Thomas, Wentworth, Emma, McDougal, Timothy A., Dussor, Gregory, Burton, Michael D, Price, Theodore J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447087/
https://ncbi.nlm.nih.gov/pubmed/30391353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.10.027
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares