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Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain

A recent major conceptual advance has been the recognition of the importance of immune system–neuronal interactions in the modulation of brain function, one example of which is spinal pain processing in neuropathic states. Here, we report that in peripheral nerve-injured rats, the lysosomal cysteine...

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Detalhes bibliográficos
Main Authors: Clark, Anna K., Yip, Ping K., Grist, John, Gentry, Clive, Staniland, Amelia A., Marchand, Fabien, Dehvari, Maliheh, Wotherspoon, Glen, Winter, Janet, Ullah, Jakir, Bevan, Stuart, Malcangio, Marzia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965568/
https://ncbi.nlm.nih.gov/pubmed/17551020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610811104
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