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SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease
SARM1 (sterile α and HEAT/armadillo motif–containing protein) is a member of the MyD88 (myeloid differentiation primary response gene 88) family, which mediates innate immune responses. Because inactivation of SARM1 prevents various forms of axonal degeneration, we tested whether it might protect ag...
Shranjeno v:
| izdano v: | J Exp Med |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Rockefeller University Press
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446871/ https://ncbi.nlm.nih.gov/pubmed/30842236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171885 |
| Oznake: |
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