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The role of macrophage scavenger receptor 1 (Msr1) in prion pathogenesis

ABSTRACT: The progression of prion diseases is accompanied by the accumulation of prions in the brain. Ablation of microglia enhances prion accumulation and accelerates disease progression, suggesting that microglia play a neuroprotective role by clearing prions. However, the mechanisms underlying t...

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Foilsithe in:J Mol Med (Berl)
Main Authors: Li, Bei, Chen, Meiling, Aguzzi, Adriano, Zhu, Caihong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Berlin Heidelberg 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164582/
https://ncbi.nlm.nih.gov/pubmed/33758958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-021-02061-7
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