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Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15
Mitotic kinesins must be regulated to ensure a precise balance of spindle forces and accurate segregation of chromosomes into daughter cells. Here, we demonstrate that kinesin-binding protein (KBP) reduces the activity of KIF18A and KIF15 during metaphase. Overexpression of KBP disrupts the movement...
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| Veröffentlicht in: | J Cell Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446846/ https://ncbi.nlm.nih.gov/pubmed/30709852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201806195 |
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