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KIF18A's neck linker permits navigation of microtubule-bound obstacles within the mitotic spindle
KIF18A (kinesin-8) is required for mammalian mitotic chromosome alignment. KIF18A confines chromosome movement to the mitotic spindle equator by accumulating at the plus-ends of kinetochore microtubule bundles (K-fibers), where it functions to suppress K-fiber dynamics. It is not understood how the...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Life Sci Alliance |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Life Science Alliance LLC
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6337737/ https://ncbi.nlm.nih.gov/pubmed/30655363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800169 |
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