Kinesin’s Neck-Linker Determines its Ability to Navigate Obstacles on the Microtubule Surface

The neck-linker is a structurally conserved region among most members of the kinesin superfamily of molecular motor proteins that is critical for kinesin’s processive transport of intracellular cargo along the microtubule surface. Variation in the neck-linker length has been shown to directly modula...

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Detalhes bibliográficos
Main Authors: Hoeprich, Gregory J., Thompson, Andrew R., McVicker, Derrick P., Hancock, William O., Berger, Christopher L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Molecular Machines, Motors and Nanoscale Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008791/
https://ncbi.nlm.nih.gov/pubmed/24739168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.02.034
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