Kinesin’s Neck-Linker Determines its Ability to Navigate Obstacles on the Microtubule Surface

The neck-linker is a structurally conserved region among most members of the kinesin superfamily of molecular motor proteins that is critical for kinesin’s processive transport of intracellular cargo along the microtubule surface. Variation in the neck-linker length has been shown to directly modula...

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Bibliografiska uppgifter
Huvudupphovsmän: Hoeprich, Gregory J., Thompson, Andrew R., McVicker, Derrick P., Hancock, William O., Berger, Christopher L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2014
Ämnen:
Molecular Machines, Motors and Nanoscale Biophysics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008791/
https://ncbi.nlm.nih.gov/pubmed/24739168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.02.034
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