Kinesin’s Neck-Linker Determines its Ability to Navigate Obstacles on the Microtubule Surface

The neck-linker is a structurally conserved region among most members of the kinesin superfamily of molecular motor proteins that is critical for kinesin’s processive transport of intracellular cargo along the microtubule surface. Variation in the neck-linker length has been shown to directly modula...

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Hlavní autoři: Hoeprich, Gregory J., Thompson, Andrew R., McVicker, Derrick P., Hancock, William O., Berger, Christopher L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2014
Témata:
Molecular Machines, Motors and Nanoscale Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008791/
https://ncbi.nlm.nih.gov/pubmed/24739168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.02.034
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