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Dynamic partitioning of mitotic kinesin-5 cross-linkers between microtubule-bound and freely diffusing states

The dynamic behavior of homotetrameric kinesin-5 during mitosis is poorly understood. Kinesin-5 may function only by binding, cross-linking, and sliding adjacent spindle microtubules (MTs), or, alternatively, it may bind to a stable “spindle matrix” to generate mitotic movements. We created transgen...

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Bibliografske podrobnosti
Main Authors: Cheerambathur, Dhanya K., Brust-Mascher, Ingrid, Civelekoglu-Scholey, Gul, Scholey, Jonathan M.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2500124/
https://ncbi.nlm.nih.gov/pubmed/18678711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804100
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