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Dynamic partitioning of mitotic kinesin-5 cross-linkers between microtubule-bound and freely diffusing states
The dynamic behavior of homotetrameric kinesin-5 during mitosis is poorly understood. Kinesin-5 may function only by binding, cross-linking, and sliding adjacent spindle microtubules (MTs), or, alternatively, it may bind to a stable “spindle matrix” to generate mitotic movements. We created transgen...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2500124/ https://ncbi.nlm.nih.gov/pubmed/18678711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804100 |
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