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The Kinesin-8 motor, Kif18A, Suppresses Kinetochore Movements to Control Mitotic Chromosome Alignment

During vertebrate cell division, chromosomes oscillate with periods of smooth motion interrupted by abrupt reversals in direction. These oscillations must be spatially constrained in order to align and segregate chromosomes with high fidelity, but the molecular mechanism for this activity is uncerta...

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Détails bibliographiques
Auteurs principaux: Stumpff, Jason, Von Dassow, George, Wagenbach, Michael, Asbury, Charles, Wordeman, Linda
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267861/
https://ncbi.nlm.nih.gov/pubmed/18267093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.11.014
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