A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A

Metaphase chromosome positioning depends on Kif18A, a kinesin-8 that accumulates at and suppresses the dynamics of K-MT plus ends. By engineering Kif18A mutants that suppress MT dynamics but fail to concentrate at K-MT plus-ends, we identify a mechanism that allows Kif18A to accumulate at K-MT plus...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Stumpff, Jason, Du, Yaqing, English, Chauca A., Maliga, Zoltan, Wagenbach, Michael, Asbury, Charles L., Wordeman, Linda, Ohi, Ryoma
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172727/
https://ncbi.nlm.nih.gov/pubmed/21884977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.07.022
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados