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Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension

Alignment of chromosomes at the metaphase plate is a signature of cell division in metazoan cells, yet the mechanisms controlling this process remain ambiguous. Here we use a combination of quantitative live cell imaging and reconstituted dynamic microtubule assays to investigate the molecular contr...

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Detalhes bibliográficos
Main Authors: Stumpff, Jason, Wagenbach, Michael, Franck, Andrew, Asbury, Charles L., Wordeman, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356572/
https://ncbi.nlm.nih.gov/pubmed/22595673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.02.013
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