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Microtubule attachment and centromeric tension shape the protein architecture of the human kinetochore

The nanoscale protein architecture of the kinetochore, a complex protein machine, plays an integral role in the molecular mechanisms underlying its functions in chromosome segregation. However, defining this architecture in human cells remains challenging because of the large size and compositional...

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Vydáno v:Curr Biol
Hlavní autoři: Kukreja, Alexander A., Kavuri, Sisira, Joglekar, Ajit. P
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755829/
https://ncbi.nlm.nih.gov/pubmed/33035484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.09.038
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