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Microtubule attachment and centromeric tension shape the protein architecture of the human kinetochore

The nanoscale protein architecture of the kinetochore, a complex protein machine, plays an integral role in the molecular mechanisms underlying its functions in chromosome segregation. However, defining this architecture in human cells remains challenging because of the large size and compositional...

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Bibliografiske detaljer
Udgivet i:Curr Biol
Main Authors: Kukreja, Alexander A., Kavuri, Sisira, Joglekar, Ajit. P
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755829/
https://ncbi.nlm.nih.gov/pubmed/33035484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.09.038
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