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How kinetochore architecture shapes the mechanisms of its function

The eukaryotic kinetochore is a sophisticated multi-protein machine that segregates chromosomes during cell division. To ensure accurate chromosome segregation, it performs three major functions using disparate molecular mechanisms. It operates a mechanosensitive signaling cascade known as the Spind...

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Publicado en:Curr Biol
Main Authors: Joglekar, Ajit P., Kukreja, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721348/
https://ncbi.nlm.nih.gov/pubmed/28829971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.06.012
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