Degradation of Blos1 mRNA by IRE1 repositions lysosomes and protects cells from stress

Cells respond to stress in the ER by initiating the widely conserved unfolded protein response. Activation of the ER transmembrane nuclease IRE1 leads to the degradation of specific mRNAs, but how this pathway affects the ability of cells to recover from stress is not known. Here, we show that degra...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Bae, Donghwi, Moore, Kristin A., Mella, Jessica M., Hayashi, Samantha Y., Hollien, Julie
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446841/
https://ncbi.nlm.nih.gov/pubmed/30787040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201809027
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