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Degradation of Blos1 mRNA by IRE1 repositions lysosomes and protects cells from stress
Cells respond to stress in the ER by initiating the widely conserved unfolded protein response. Activation of the ER transmembrane nuclease IRE1 leads to the degradation of specific mRNAs, but how this pathway affects the ability of cells to recover from stress is not known. Here, we show that degra...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446841/ https://ncbi.nlm.nih.gov/pubmed/30787040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201809027 |
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