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Degradation of Blos1 mRNA by IRE1 repositions lysosomes and protects cells from stress
Cells respond to stress in the ER by initiating the widely conserved unfolded protein response. Activation of the ER transmembrane nuclease IRE1 leads to the degradation of specific mRNAs, but how this pathway affects the ability of cells to recover from stress is not known. Here, we show that degra...
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| Udgivet i: | J Cell Biol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Rockefeller University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446841/ https://ncbi.nlm.nih.gov/pubmed/30787040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201809027 |
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