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Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells

BACKGROUND: Solid tumours are less oxygenated than normal tissues. This is called tumour hypoxia and leads to resistance to radiotherapy and chemotherapy. The molecular mechanisms underlying such resistance have been investigated in a range of tumour types, including the adult brain tumours glioblas...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Cowman, Sophie, Fan, Yuen Ngan, Pizer, Barry, Sée, Violaine
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446413/
https://ncbi.nlm.nih.gov/pubmed/30943920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5476-9
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