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Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells

BACKGROUND: Solid tumours are less oxygenated than normal tissues. This is called tumour hypoxia and leads to resistance to radiotherapy and chemotherapy. The molecular mechanisms underlying such resistance have been investigated in a range of tumour types, including the adult brain tumours glioblas...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Cowman, Sophie, Fan, Yuen Ngan, Pizer, Barry, Sée, Violaine
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446413/
https://ncbi.nlm.nih.gov/pubmed/30943920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5476-9
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