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Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells

BACKGROUND: Solid tumours are less oxygenated than normal tissues. This is called tumour hypoxia and leads to resistance to radiotherapy and chemotherapy. The molecular mechanisms underlying such resistance have been investigated in a range of tumour types, including the adult brain tumours glioblas...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Cowman, Sophie, Fan, Yuen Ngan, Pizer, Barry, Sée, Violaine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446413/
https://ncbi.nlm.nih.gov/pubmed/30943920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5476-9
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