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Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells

BACKGROUND: Solid tumours are less oxygenated than normal tissues. This is called tumour hypoxia and leads to resistance to radiotherapy and chemotherapy. The molecular mechanisms underlying such resistance have been investigated in a range of tumour types, including the adult brain tumours glioblas...

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Podrobná bibliografie
Vydáno v:BMC Cancer
Hlavní autoři: Cowman, Sophie, Fan, Yuen Ngan, Pizer, Barry, Sée, Violaine
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446413/
https://ncbi.nlm.nih.gov/pubmed/30943920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5476-9
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