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Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells

BACKGROUND: Solid tumours are less oxygenated than normal tissues. This is called tumour hypoxia and leads to resistance to radiotherapy and chemotherapy. The molecular mechanisms underlying such resistance have been investigated in a range of tumour types, including the adult brain tumours glioblas...

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Pubblicato in:BMC Cancer
Autori principali: Cowman, Sophie, Fan, Yuen Ngan, Pizer, Barry, Sée, Violaine
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446413/
https://ncbi.nlm.nih.gov/pubmed/30943920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5476-9
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