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Beyond sensing DNA: a role for cGAS in the detection of extracellular cyclic di‐nucleotides
Cyclic GMP‐AMP synthase (cGAS) is best known as an innate immune receptor that detects pathogen DNA in the cytosol. In this issue of EMBO Reports, Kaufmann and colleagues 1 report that cGAS has an additional role in innate immunity: it can also bind cyclic di‐nucleotides (CDNs), signalling molecules...
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| Vydáno v: | EMBO Rep |
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| Hlavní autor: | |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446196/ https://ncbi.nlm.nih.gov/pubmed/30890539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201947970 |
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