Adenovirus Detection by the cGAS/STING/TBK1 DNA Sensing Cascade

Adenovirus (Ad) infection triggers a cell-specific antiviral response following exposure of viral DNA to the intracellular compartment. A variety of DNA sensors (DAI, AIM2, DDx41, RNA polymerase [Pol] III, and IFI16 [p204]) have been identified in recent years; however, the DNA sensor involved in de...

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Bibliographic Details
Main Authors: Lam, Eric, Stein, Saskia, Falck-Pedersen, Erik
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911663/
https://ncbi.nlm.nih.gov/pubmed/24198409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02702-13
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