Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors

The ubiquitin-proteasome system has been largely investigated for its key role in protein degradation mechanisms that regulate both apoptosis and cell division. Because of their antitumour activity, different classes of proteasome inhibitors have been identified to date. Some of these compounds are...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Marastoni, Mauro, Trapella, Claudio, Scotti, Alessandra, Fantinati, Anna, Ferretti, Valeria, Marzola, Erika, Eleonora, Gallerani, Gavioli, Riccardo, Preti, Delia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445160/
https://ncbi.nlm.nih.gov/pubmed/28657369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1334649
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