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Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors

The ubiquitin-proteasome system has been largely investigated for its key role in protein degradation mechanisms that regulate both apoptosis and cell division. Because of their antitumour activity, different classes of proteasome inhibitors have been identified to date. Some of these compounds are...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Enzyme Inhib Med Chem
Prif Awduron: Marastoni, Mauro, Trapella, Claudio, Scotti, Alessandra, Fantinati, Anna, Ferretti, Valeria, Marzola, Erika, Eleonora, Gallerani, Gavioli, Riccardo, Preti, Delia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445160/
https://ncbi.nlm.nih.gov/pubmed/28657369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1334649
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