Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors

The ubiquitin-proteasome system has been largely investigated for its key role in protein degradation mechanisms that regulate both apoptosis and cell division. Because of their antitumour activity, different classes of proteasome inhibitors have been identified to date. Some of these compounds are...

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Bibliographic Details
Published in:J Enzyme Inhib Med Chem
Main Authors: Marastoni, Mauro, Trapella, Claudio, Scotti, Alessandra, Fantinati, Anna, Ferretti, Valeria, Marzola, Erika, Eleonora, Gallerani, Gavioli, Riccardo, Preti, Delia
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445160/
https://ncbi.nlm.nih.gov/pubmed/28657369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1334649
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