Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors

[Image: see text] Proteasome activity affects cell cycle progression as well as the immune response, and it is largely recognized as an attractive pharmacological target for potential therapies against several diseases. Herein we present the synthesis of a series of pseudodi/tripeptides bearing at t...

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Vydáno v:ACS Med Chem Lett
Hlavní autoři: Pacifico, Salvatore, Ferretti, Valeria, Albanese, Valentina, Fantinati, Anna, Gallerani, Eleonora, Nicoli, Francesco, Gavioli, Riccardo, Zamberlan, Francesco, Preti, Delia, Marastoni, Mauro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2019
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627721/
https://ncbi.nlm.nih.gov/pubmed/31312413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00233
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