Impaired Priming of SARS-CoV-2-Specific Naive CD8(+) T Cells in Older Subjects

Advanced age is associated with severe symptoms and death upon SARS-CoV-2 infection. Virus-specific CD8(+) T-cell responses have shown to be protective toward critical COVID-19 manifestations, suggesting that suboptimal cellular immunity may contribute to the age-pattern of the disease. The inductio...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gallerani, Eleonora, Proietto, Davide, Dallan, Beatrice, Campagnaro, Marco, Pacifico, Salvatore, Albanese, Valentina, Marzola, Erika, Marconi, Peggy, Caputo, Antonella, Appay, Victor, Gavioli, Riccardo, Nicoli, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315546/
https://ncbi.nlm.nih.gov/pubmed/34326844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.693054
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