The HIV-1 Tat Protein Induces the Activation of CD8(+) T Cells and Affects In Vivo the Magnitude and Kinetics of Antiviral Responses

T cells are functionally compromised during HIV infection despite their increased activation and proliferation. Although T cell hyperactivation is one of the best predictive markers for disease progression, its causes are poorly understood. Anti-tat natural immunity as well as anti-tat antibodies in...

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Detalhes bibliográficos
Main Authors: Nicoli, Francesco, Finessi, Valentina, Sicurella, Mariaconcetta, Rizzotto, Lara, Gallerani, Eleonora, Destro, Federica, Cafaro, Aurelio, Marconi, Peggy, Caputo, Antonella, Ensoli, Barbara, Gavioli, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817196/
https://ncbi.nlm.nih.gov/pubmed/24223723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077746
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